2009
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PR Newswire, Dec 2, 2009
BIRMINGHAM, Ala., Dec. 2 /PRNewswire/ — Adults are more likely to lose their vision than be diagnosed with cancer. For adults 65 and over, the odds of losing vision are one in three, whereas the odds of a man developing prostate cancer are one in six and odds of a woman developing breast cancer are one in nine. Vision loss threatens the overall health of aging adults by increasing the risk of injuries, depression and inability to complete daily tasks.
Vision loss in adults is often attributed to age-related macular degeneration (AMD), a breakdown of the macula that destroys sharp, central vision. Damage to the macula causes blurriness and distortion of vision, which can affect the ability to see fine details clearly. AMD is the leading cause of blindness in American adults and affects millions of aging adults worldwide.
Though there is currently no cure for AMD, sufferers and aging adults can prevent the development or progression of the disease with proper nutrition. A study conducted at the Callahan Eye Foundation Hospital of Birmingham, Alabama revealed that AMD sufferers taking a specific eye vitamin supplement, Macular Health, showed both short-term and long-term improvement in visual acuity by 16 and 17 percent. Researchers attribute the improvement to Macular Health’s specific dosage of lutein, zeaxanthin and bilberry, and the administration of specific carotenoids, vitamins and minerals.
As quoted in Ophthalmology Times, the creator of Macular Health, Dr
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Market Wire, December, 2009
Editors Note: A photo for this release will be available on the CP picture wire
via Marketwire.
Montreal Alouettes’ Quarterback Anthony Calvillo, winner of the Gibson’s Finest Most Outstanding Player Award, will donate the $10,000 award provided by Gibson’s Finest Canadian Whisky to The Cedars Cancer Institute at the McGill University Health Centre (MUHC). Calvillo chose Cedars in honour of his wife, Alexia, who was recently treated at the MUHC for B-cell lymphoma and is now in remission.
The money will help renovate the Family Room on the oncology floor of the Montreal General Hospital. The renovation project will include new furniture, a computer and television among other improvements.
“My wife battled cancer at the Royal Victoria Hospital and we used the family room a lot when people would visit us. It was the only place you could go and not think about the treatments,” says Calvillo. “When my wife was in remission and healthy we decided to do something special. The family room needed to be updated so we decided to take this on as a project. Now we want to make sure patients and their families at the Montreal General Hospital have a comfortable and welcoming space too.”
Alexia went into remission last February, and Calvillo says he was “blown away” by the charity donation amount given to him by Gibson’s Finest.
“There are so many charities out there and to be able to be part of one that touched our family’s hearts is really overwhelming. We hope that other families join us so that together we can complete this project for the benefit of cancer patients and their loved ones,” says Calvillo.
The cheque presentation will take place on Tuesday, December 15 at 10:00 a.m
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Chemistry and Industry, Feb 9, 2009 by Sarah Houlton
The incidence of diabetes is increasing at an alarming rate. According to World Health Organization estimates, at least 171m people worldwide had the condition n one of its forms in 2000, and it expects this to more than double Dy 2030. There are two main forms: in Type 1, little or no insulin is produced by the pancreas, so regular doses of insulin are required; and in Type 2, by far the most common form, the body is unable to use its insulin effectively. Type 2 can frequently De managed by diet and exercise, but often drugs are required, and sometimes insulin s needed too.
Those diabetics who require insulin face a lifetime of injections. While modern injectors are easy to use and have very fine needles which limit the pain, regular injections are intrusive, and several non-injected forms are being investigated, notably inhaled and oral forms. ‘Non-injected insulin could, potentially, improve the quality of life for many people with diabetes, particularly those with needle phobias,’ claims Pav Kalsi, care advisor at Diabetes UK. ‘Inhaled or oral insulin could reduce the need for multiple injections and therefore have less of an impact on day to day life.’
However, the lifestyle impact is not the only driver behind the search for non-injected insulin–while insulin injections are life-saving, they do not mimic the way insulin acts in the body as well as they might. Insulin pumps offer a better profile, but they are also intrusive, as the device has to be worn all the time.
One inhaled insulin product has already reached the market. Exubera, marketed by Pfizer and developed in conjunction with Nektar Therapeutics, was approved in 2006, but never gained widespread acceptance. This was partly because the extra cost was not justified by substantial advantages over standard insulin, but mainly because the delivery device was far too big. It was withdrawn from the market a year later, and in the wake of this, both Novo Nordisk working with Aradigm, and Eli Lilly with Alkermes, stopped development work on their inhaled insulin products.
This was not the end for inhaled insulin, however–MannKind has pressed ahead with the development of its own version, Afresa, in which a small organic molecule, fumaryl diketopiperazine (FDKP), is used to create inhalable particles. ‘This molecule dissolves in water under basic conditions,’ explains the company’s vice president of pharmaceutical development, Andrea Leone–Bay. ‘Subsequent acid-induced precipitation produces nanocrystals that self-assemble into microparticles. These Technosphere particles are exactly the right size for inhalation into the deep lung. We then adsorb insulin onto the particle surfaces.’ Diketopiperazines are known to self-assemble like this in solution, but FDKP is unusual as it forms particles that retain their structural integrity when dry.
FDKP is soluble at pH 7, very close to physiological pH, so when the particle hits the surface of the lung, it dissolves in the lung fluid. ‘The insulin is rapidly absorbed into the body by natural mechanisms, and the FDKP is excreted unchanged, primarily in the urine, as it is not metabolised,’ Leone-Bay says.
Another key feature is the rapidity of absorption, and the lack of variability of absorption compared with subcutaneous or other routes, chief scientific officer Peter Richardson explains. ‘The best that has been achieved with rapid-acting injected insulin analogues is an onset of action of around 40 minutes to an hour,’ he says. ‘With Afresa, the onset of insulin action is 12-14 minutes, which is much closer to the normal physiological response of 5-6 minutes or so. It’s a considerable difference.’
This is reflected in the changes in glucose production in the liver and the body, and consequently in the early changes after a meal in terms of the rate at which glucose levels rise after eating
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0 Comments | Todmorden News (Todmorden, England), Dec 3, 2009
Sports took the lead but within minutes, the Stars equalised.
However, it was Sports who had the better of the half and could have retaken the lead, hitting a post and seeing a stunning triple save by the home goalkeeper keep the scores level.
Sports were finally rewarded by retaking the lead just before the break but Stars equalised midway through the second half, the TSC keeper fumbling a long range effort into the net.
Stars netted again but with just minutes left TSC were denied again by the inspired home goalkeeper and had a goalbound effort cleared off the line before a classic counter attack saw the home striker complete his hat trick in the final minute.
TODMORDEN Sports Centre under-12 battled hard before losing 4-2 to Greetland Stars in the Calderdale Junior League Cup.
Sports took the lead but within minutes, the Stars equalised.
However, it was Sports who had the better of the half and could have retaken the lead, hitting a post and seeing a stunning triple save by the home goalkeeper keep the scores level.
Sports were finally rewarded by retaking the lead just before the break but Stars equalised midway through the second half, the TSC keeper fumbling a long range effort into the net.
Stars netted again but with just minutes left TSC were denied again by the inspired home goalkeeper and had a goalbound effort cleared off the line before a classic counter attack saw the home striker complete his hat trick in the final minute.
0 Comments | Manila Bulletin, Dec 7, 2009
Two family cooks, four yayas, a driver, and handyman who had served the Estradas for more than three decades joined the children of former President Joseph Estrada and First Lady Luisa Ejercito-Estrada who celebrated their golden wedding anniversary last Sunday in the quaint terrains of Tanay, Rizal where the former president was detained for almost seven years.Dressed in formal wear, they marched with Senate President Pro Tempore Jinggoy Estrada, his sister Jackie, and youngest sibling Jude and their children in the red carpet of the tiny chapel to begin what mass celebrant Msgr.
Albert Venus described as the Estradas 50th-year celebration of the gifts of love, joy, pain and sorrow.Waiting at the altar were Senate President Juan Ponce Enrile and wife, Mrs. Cristina Castaner-Enrile, Senator Miriam Defensor-Santiago, and former Supreme Court Chief Justice Andres Narvasa who stood as sponsors for the famous couple.Household cook Paz Tullay, now 69 years old, linked hands with fellow cook Mercy Gratuita, Dolores Custodio, Leonora de Joseph, driver Arnel Giron who married to Estradas girl Friday, Merle, and Jun Abarra, the handyman, during the celebrations.They all had served the Estradas for at least three decades, with most of them staying with their families in the Estrada compound in North Greenhills.Members of Estradas Cabinet who had stood by their Commander-in-Chief through all the good and bad times together with their spouses, were also in attendance in the flower-decked chapel as the celebrators reaffirmed their commitment to one another amid the memory of joys and sorrows they have shared together for half a century.An emotional Estrada, dressed in Barong Tagalog, with the deeply-religious Dra. Loi on his arms, marched to the altar to formally start the golden wedding rites amid a backdrop of heart-warming applause from the intimate gathering of family and loyal friends.Following the mass, the Estradas received the nuptial blessings from the celebrating priests that Divine Providence continue to fill them with everlasting joy until they enter into their heavenly inheritance.The mass over, Estrada kissed his bride of 50 years on both cheeks, tightly hugging her in a rain of petals of white roses and rice strewn at their path. They then turned around to face their guests and bowed to their joyful ring of applause, cheers and good wishes for what the future holds for them.At the reception that followed at the Estradas Tanay resthouse which is now a tourist destination, the couple mingled with guests to the strains of Always You, their love song.In a brief unrehearsed talk in the course of the reception, Estrada chronicled his life with the former First Lady and Senator which he said began more than fifty years ago after he met and fell for his future bride at the then National Mental Hospital where he was working as a casual employee.He mentioned that his work as a mimeographer at the hospital was his third job following his stint as a timekeeper at the Galaxy Theatre on Rizal Avenue in Manila, and as an ambulance driver at the San Lazaro Hospital.I was struggling to earn my own money, and was not allowed to use any of the two family vehicles assigned for the exclusive use of my elder brothers and sisters, Estrada said.He later learned that Drs. Lois favorite was a half-order of Max chicken, and borrowing an old jeep that was almost a junk, he invited her to dinner over a whole order of Max chicken.The popular opposition leader admitted that his future bride was ostracized by the hospital hierarchy for entertaining Estrada as a suitor.It became a challenge to me, and I could only imagine how it felt for Dra
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PR Newswire, Dec 1, 2009
COLUMBUS, Ohio, Dec. 1 /PRNewswire-FirstCall/ — In conjunction with Limited Brands’ November sales release, you are invited to listen to a broadcast of its sales call with Amie Preston, Vice President of Investor Relations for Limited Brands . The broadcast will be available on the Internet on Thursday, December 3, at 7:30 a.m. ET.
(Logo: http://www.newscom.com/cgi-bin/prnh/20020520/CLM001LOGO )What: Limited Brands November Sales Report
When: December 3, 2009 at 7:30 a.m
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Huddersfield Daily Examiner (Huddersfield, England), Dec 2, 2009
THE Met Office said last month was the wettest November on record with an average of 217.4mm of rain across the UK.
The previous record of 193.6mm dated back to 1951.
The Met Office weather station which recorded the highest rainfall last month was in Shap, Cumbria, with 621.4mm.
Rain caused chaos in Cumbria last month as floodwater forced hundreds of people from their homes and businesses.
Today’s statistics show that rainfall last month also set a new record of 197.6mm for England and Wales, breaking the previous high of 196.9mm which had stood since 1929.
CAPTION(S):
* FLOATING CITY: Sandbags and pumps keep the floodwater under control as York experiences serious flooding, which has closed several main roads
0 Comments | Western Daily Press, Dec 3, 2009
The FTSE 100 Index held on to gains seen in Tuesday’s bounce- back yesterday as heavyweight stocks lent their support.
Record gold prices saw commodity shares race to the top of the risers’ board.
Gains among blue chip companies such as Vodafone also helped the Footsie consolidate Tuesday’s 2.3 per cent surge.
The top tier closed 15.2 points higher at 5327.4 as investor confidence continued to hold up amid relief over the global impact of Dubai’s debt crisis.
The Dow Jones Industrial Average on Wall Street was pausing for breath in early trade after it too rallied in the previous session – closing at its highest level since October last year as global markets shrugged off fears over debt-ridden Dubai.
There was little in the way of corporate news, but a new high for gold prices put the spotlight on miners again in London.
Gold hit around 1,217 dollars an ounce as the US dollar continued to be snubbed by investors, which saw Lonmin leap to the top of the risers board with a three per cent gain, up 60p to 1911p.
Rio Tinto and Vedanta Resources followed its lead, with gains of 82p at 3292p and 59p at 2445p respectively.
A more than two per cent gain for Vodafone also saw the mobile phone giant earn its place on the leaders board, up 3.05p at 143.05p.
Royal Bank of Scotland was one of the top flight’s biggest fallers – down two per cent – after a national newspaper claimed the Treasury had demanded control of Royal Bank of Scotland’s bonus pot.
Investors snub the dollar
0 Comments | The Virginian-Pilot and The Ledger-Star, Norfolk, VA, Feb 20, 2009 | by JANE ENGLE
leave the airport
Rental cars at airports typically have higher rates and a host of fees and taxes that aren’t charged elsewhere . Your chances of landing a weekend discount improve away from the airport. Take a cab to where you’re going and rent a car, unless the cab fare is $50, or consider using public transportation.
avoid the extras
Waivers and insurance to cover collision damage, liability and loss of personal effects can total $25 or more each day when bought at the rental desk. Yet, in many cases, you don’t need this coverage because it’s already provided by your auto, homeowner’s or renter’s policies
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